This handbook concisely summarizes state-of-the-art information about stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), including the history and development of these modalities, the biologic rationale for these technologies, typical practices, and reported results. Developed as a companion toHandbook of Evidence-Based Radiation Oncology, edited by Eric Hansen and Mack Roach, III, it is organized by disease site and presents treatment techniques and recommended imaging; safety and quality assurance; toxicities and management; recommended follow-up; and supporting evidence. Inclusion of evidence-based guidelines is intended to help inform decisions regarding the appropriateness of SRS and SBRT and guide treatment and evaluation. This new edition is fully updated with the latest literature. A new chapter on dose constraints has also been added, along with additional content on SBRT for oligometastatic disease and prostate, and the integration of SBRT with systemic therapy, including chemotherapy, immunotherapy, targeted agents. Case examples are added, as well as additional images to highlight situations described.Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy, 2e can be easily referenced in the clinic and is a valuable guide for radiation oncology practitioners

Rajni Sethi, MD is a radiation oncologist at Kaiser Permanente.

Igor J. Barani, MD is an Associate Professor and Chair of the Department of Radiation Oncology at Barrow Neurological Institute.

David A. Larson, MD, PhD is Professor Emeritus of Radiation Oncology at University of California, San Francisco.

Mack Roach III, MD is Professor of Radiation Oncology and Urology at University of California, San Francisco. He is co-editor of theHandbook of Evidence-Based Radiation Oncology, 3e (2018).

Introduction to Stereotactic Radiosurgery and Stereotactic Body Radiotherapy.- Part I Radiobiology of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy.- Radiobiology of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy.- Part II Physics of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy.- Physics of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy.- Part III Clinical Applications.- Intracranial Tumors.- Spine.- Head and Neck.- Lung.- Digestive System.- Genitourinary Sites.- Gynecologic Sites.- Soft Tissue Sarcoma.- Extracranial Oligometastases.- Dose Constraints and Planning.